Dysfunction of bloodbrain barrier and intrathecal immune response in patients with clinically isolated multiple sclerosis syndrome
نویسندگان
چکیده
منابع مشابه
Multiple sclerosis lesions evolution in patients with clinically isolated syndrome
Multiple sclerosis (MS) is a disease with heterogeneous evolution among the patients. Some classifications have been carried out according to either the clinical course or the immunopathological profiles. Epidemiological data and imaging are showing that MS is a two-phase neurodegenerative inflammatory disease. At the early stage it is dominated by focal inflammation of the white matter (WM), a...
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Background: Clinical course of Clinically Isolated Syndrome (CIS) is variable, and identifying patients who will eventually develop Multiple Sclerosis (MS) is essential. Objectives: To assess the conversion rate of CIS to Clinically Definite Multiple Sclerosis (CDMS) and its predictors in southern Iran. Materials & Methods: A total of 143 CIS patients registered to Fars Multiple Sclerosis Soc...
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Multiple Sclerosis (MS) is one of the most common diseases of the central nervous system it is often seen in adults who may be sexually active. This disability can be associated with sexual-urinary problems that affect all aspects of their lives. The aim of this study is to evaluate the association between disability and urinary-sexual dysfunction in women with MS. This study is a descriptive-c...
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Background: Cell-derived microparticles are secreted in response to cell damage or dysfunction. Endothelial and platelet dysfunction are thought to contribute to the development of multiple sclerosis (MS). Our aim here is, first, to compare the presence of microparticles of endothelial and platelet origin in plasma from patients with different clinical forms of MS and with clinically isolated s...
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BACKGROUND Cognitive impairment (CI) is a frequent symptom of multiple sclerosis (MS); its prevalence is reported to be 43-70%. It is one of the most important determinants of MS patients' quality of life, as it is one of the main factors for MS patients becoming unemployed. AIM We aimed to determine the prevalence of CI among the relapsing-remitting MS (RRMS) and clinically isolated syndrome...
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ژورنال
عنوان ژورنال: Ukrains'kyi Visnyk Psykhonevrolohii
سال: 2019
ISSN: 2079-0325
DOI: 10.36927/2079-0325-v27-is2-2019-4